Influence of Early Experience on Adult Brain Organization and Function

Event Dates (Pacific Time): 
Friday, December 2, 2016 - 1:00pm to 5:30pm
Event Chairs:

Terry Sejnowski, Salk Institute for Biological Studies
Carla Shatz, Stanford University

Early experience impacts adult brain structure and function but the extent of this influence and the mechanisms by which developmental neuronal plasticity affects adult brain function are unclear. Discussions of healthy and dysregulated development will help to define the questions that will be further addressed in animal models, and mechanisms responsible for developmental consequences will be analyzed at cellular and molecular levels. Some of the questions that will be addressed include: How do events of early development show up in our behavior as we age? What are the opportunities and risks during early development and their consequences for adult behavior? Can the identification of windows of “critical periods” in early development be used to reopen these windows at later points in the lifetime to enhance or regenerate adult function? The developmental origins of neurological and psychiatric disorders will frame many of the issues being addressed in this symposium.

Event Sessions

Media for each talk can be played by clicking on icons in the "Media" column, or by clicking on the individual talk titles below and then the attachment file at the bottom of the page.

Speakers Media Session Title

Nick Spitzer
University of California, San Diego (UCSD)

Terry Sejnowski
Salk Institute for Biological Studies
File Welcome & Opening Remarks

April Benasich
Rutgers University-Newark
File Early Brain Trajectories & Evolving Oscillations: Template for Mature Function?

BJ Casey
Yale University
File The Effects of Early Life Stress on Brain and Behavior

Catherine Dulac
Harvard University
File Neurobiology of the Parental Brain

Jay Giedd
University of California, San Diego (UCSD)
File The Amazing Teen Brain

Carla Shatz
Stanford University
File Making an Old Brain Young? From Developmental Critical Periods to Alzheimer’s Disease

Beth Stevens
Harvard Medical School - Boston Children's Hospital
File How Immune Cells Sculpt Developing Synaptic Circuits

Mark Bear
Massachusetts Institute of Technology
File Using Neurobiology to Overcome Genetic and Environmental Adversity

Matthew State
University of California, San Francisco (UCSF)
File Tracing the Path from Spontaneous Mutation to Neurobiology in Autism Spectrum Disorders

Terry Sejnowski
Salk Institute for Biological Studies
File The Challenge of Integration

Carla Shatz
Stanford University

Fred Gage
Salk Institute for Biological Studies
File Question and Answer Session, Closing Remarks