Sarkis Mazmanian

The Sarkis laboratory focuses on three major areas of study:

1. Identify the molecular components of the host immune system which recognize and respond to the immunomodulatory signals of symbiotic bacteria.

2. Define the cellular and molecular mechanisms which mediate protection to immune pathologies such as colitis.

3. Explore the possibility of harnessing the beneficial effects provided by symbiotic bacteria for the development of therapies against immune-mediated disorders.