@article {1679,
	title = {The marmoset monkey as a model for visual neuroscience.},
	journal = {Neurosci Res},
	volume = {93},
	year = {2015},
	month = {2015 Apr},
	pages = {20-46},
	abstract = {<p>The common marmoset (Callithrix jacchus) has been valuable as a primate model in biomedical research. Interest in this species has grown recently, in part due to the successful demonstration of transgenic marmosets. Here we examine the prospects of the marmoset model for visual neuroscience research, adopting a comparative framework to place the marmoset within a broader evolutionary context. The marmoset{\textquoteright}s small brain bears most of the organizational features of other primates, and its smooth surface offers practical advantages over the macaque for areal mapping, laminar electrode penetration, and two-photon and optical imaging. Behaviorally, marmosets are more limited at performing regimented psychophysical tasks, but do readily accept the head restraint that is necessary for accurate eye tracking and neurophysiology, and can perform simple discriminations. Their natural gaze behavior closely resembles that of other primates, with a tendency to focus on objects of social interest including faces. Their immaturity at birth and routine twinning also makes them ideal for the study of postnatal visual development. These experimental factors, together with the theoretical advantages inherent in comparing anatomy, physiology, and behavior across related species, make the marmoset an excellent model for visual neuroscience.</p>
},
	keywords = {Animals, Biological Evolution, Brain, Callithrix, Color Perception, Color Vision, Exploratory Behavior, Macaca, Models, Animal, Social Behavior, Vision, Binocular, Vision, Ocular, Visual Perception},
	issn = {1872-8111},
	doi = {10.1016/j.neures.2015.01.008},
	author = {Mitchell, Jude F and Leopold, David A}
}
@article {198,
	title = {Active vision in marmosets: a model system for visual neuroscience.},
	journal = {J Neurosci},
	volume = {34},
	year = {2014},
	month = {2014 Jan 22},
	pages = {1183-94},
	abstract = {<p>The common marmoset (Callithrix jacchus), a small-bodied New World primate, offers several advantages to complement vision research in larger primates. Studies in the anesthetized marmoset have detailed the anatomy and physiology of their visual system (Rosa et al., 2009) while studies of auditory and vocal processing have established their utility for awake and behaving neurophysiological investigations (Lu et al., 2001a,b; Eliades and Wang, 2008a,b; Osmanski and Wang, 2011; Remington et al., 2012). However, a critical unknown is whether marmosets can perform visual tasks under head restraint. This has been essential for studies in macaques, enabling both accurate eye tracking and head stabilization for neurophysiology. In one set of experiments we compared the free viewing behavior of head-fixed marmosets to that of macaques, and found that their saccadic behavior is comparable across a number of saccade metrics and that saccades target similar regions of interest including faces. In a second set of experiments we applied behavioral conditioning techniques to determine whether the marmoset could control fixation for liquid reward. Two marmosets could fixate a central point and ignore peripheral flashing stimuli, as needed for receptive field mapping. Both marmosets also performed an orientation discrimination task, exhibiting a saturating psychometric function with reliable performance and shorter reaction times for easier discriminations. These data suggest that the marmoset is a viable model for studies of active vision and its underlying neural mechanisms.</p>
},
	keywords = {Animals, Callithrix, Conditioning, Operant, Models, Animal, Neurophysiology, Neurosciences, Saccades, Vision, Ocular, Visual Perception},
	issn = {1529-2401},
	doi = {10.1523/JNEUROSCI.3899-13.2014},
	author = {Mitchell, Jude F and Reynolds, John H and Miller, Cory T}
}
