@article {174,
	title = {Adult neurogenesis: integrating theories and separating functions.},
	journal = {Trends Cogn Sci},
	volume = {14},
	year = {2010},
	month = {2010 Jul},
	pages = {325-37},
	abstract = {<p>The continuous incorporation of new neurons in the dentate gyrus of the adult hippocampus raises exciting questions about memory and learning, and has inspired new computational models to understand the function of adult neurogenesis. These theoretical approaches suggest distinct roles for new neurons as they slowly integrate into the existing dentate gyrus network: immature adult-born neurons seem to function as pattern integrators of temporally adjacent events, thereby enhancing pattern separation for events separated in time; whereas maturing adult-born neurons possibly contribute to pattern separation by being more amenable to learning new information, leading to dedicated groups of granule cells that respond to experienced environments. We review these hypothesized functions and supporting empirical research and point to new directions for future theoretical efforts.</p>
},
	keywords = {Adult, Adult Stem Cells, Animals, Cell Proliferation, Hippocampus, Humans, Models, Biological, Neurogenesis, Neurons},
	issn = {1879-307X},
	doi = {10.1016/j.tics.2010.04.003},
	author = {Aimone, James B and Deng, Wei and Gage, Fred H}
}
@article {182,
	title = {New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?},
	journal = {Nat Rev Neurosci},
	volume = {11},
	year = {2010},
	month = {2010 May},
	pages = {339-50},
	abstract = {<p>The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an important role for adult hippocampal neurogenesis in learning and memory, but its specific function in these processes has remained elusive. In this article, we summarize recent progress in this area, including advances based on behavioural studies and insights provided by computational modelling. Increasingly, evidence suggests that newborn neurons might be involved in hippocampal functions that are particularly dependent on the dentate gyrus, such as pattern separation. Furthermore, newborn neurons at different maturation stages may make distinct contributions to learning and memory. In particular, computational studies suggest that, before newborn neurons are fully mature, they might function as a pattern integrator by introducing a degree of similarity to the encoding of events that occur closely in time.</p>
},
	keywords = {Adult Stem Cells, Animals, Hippocampus, Humans, Learning, Memory, Models, Neurological, Neurogenesis, Neurons},
	issn = {1471-0048},
	doi = {10.1038/nrn2822},
	author = {Deng, Wei and Aimone, James B and Gage, Fred H}
}
