@article {1788,
	title = {Imaging brain activity during complex social behaviors in Drosophila with Flyception2.},
	journal = {Nat Commun},
	volume = {11},
	year = {2020},
	month = {2020 01 30},
	pages = {623},
	abstract = {<p>Optical in vivo recordings from freely walking Drosophila are currently possible only for limited behaviors. Here, we expand the range of accessible behaviors with a retroreflective marker-based tracking and ratiometric brain imaging system, permitting brain activity imaging even in copulating male flies. We discover that P1 neurons, active during courtship, are inactive during copulation, whereas GABAergic mAL neurons remain active during copulation, suggesting a countervailing role of mAL in opposing P1 activity during mating.</p>
},
	keywords = {Animals, Brain, Copulation, Courtship, Drosophila, Drosophila Proteins, Female, GABAergic Neurons, Male, Neuroimaging, Neurons, Olfactory Cortex, Sexual Behavior, Animal, Social Behavior},
	issn = {2041-1723},
	doi = {10.1038/s41467-020-14487-7},
	author = {Grover, Dhruv and Katsuki, Takeo and Li, Jinfang and Dawkins, Thomas J and Greenspan, Ralph J}
}
@article {163,
	title = {Genes involved in sex pheromone discrimination in Drosophila melanogaster and their background-dependent effect.},
	journal = {PLoS One},
	volume = {7},
	year = {2012},
	month = {2012},
	pages = {e30799},
	abstract = {<p>Mate choice is based on the comparison of the sensory quality of potential mating partners, and sex pheromones play an important role in this process. In Drosophila melanogaster, contact pheromones differ between male and female in their content and in their effects on male courtship, both inhibitory and stimulatory. To investigate the genetic basis of sex pheromone discrimination, we experimentally selected males showing either a higher or lower ability to discriminate sex pheromones over 20 generations. This experimental selection was carried out in parallel on two different genetic backgrounds: wild-type and desat1 mutant, in which parental males showed high and low sex pheromone discrimination ability respectively. Male perception of male and female pheromones was separately affected during the process of selection. A comparison of transcriptomic activity between high and low discrimination lines revealed genes not only that varied according to the starting genetic background, but varied reciprocally. Mutants in two of these genes, Shaker and quick-to-court, were capable of producing similar effects on discrimination on their own, in some instances mimicking the selected lines, in others not. This suggests that discrimination of sex pheromones depends on genes whose activity is sensitive to genetic context and provides a rare, genetically defined example of the phenomenon known as "allele flips," in which interactions have reciprocal effects on different genetic backgrounds.</p>
},
	keywords = {Animals, Animals, Genetically Modified, Behavior, Animal, Breeding, Courtship, Drosophila melanogaster, Female, Genes, Insect, Male, Mutation, Olfactory Perception, Reproduction, Sex Attractants, Sexual Behavior, Animal, Species Specificity},
	issn = {1932-6203},
	doi = {10.1371/journal.pone.0030799},
	author = {Houot, Benjamin and Fraichard, St{\'e}phane and Greenspan, Ralph J and Ferveur, Jean-Fran{\c c}ois}
}
